"Research of correlation of characteristic symptoms and indexes of ""brain collateral damage"" at acute stage of stroke" / 国际中医中药杂志

ABSTRACT

ObjectiveTo explore the correlation of characteristic symptoms and indexes of brain collateral damageat acute stage of stroke.MethodsSeventy cases who got stroke within 72 hours were included.Five nonspecific symptoms and 6 indexes were observed at two time points.ResultsThere were positive correlations between the number of nonspecific symptoms and the value of Hs-CRP,IL-6,OX-LDL,NSE.The correlation coefficients were 0.307,0.289,0.342,0.253 and P＜0.05.Nonspecific symptoms appeared in 1 to 3 groups,altogether 40 cases were involved,and the groups had significant deviation compared with the groupwithoutnonspecificsymptomsonOX-LDL(32.37 ± 31.17)μg/l, NSE(2.82 ± 1.25)ng/ml,MMP-9 (214.97± 137.88) ng/ml and P＜0.05.Single symptom especially dull expression and hypersomnia were proved to be related with the indexes.For example,the correlation coefficient was 0.318 between hypersomnia and Hs-CRP.The correlation coefficient was 0.384 between dull expression and IL-6.Conclusion Characteristic symptoms were well correlated and ganged with the indexes from different view or level.It acted as representative combination of brain collateral damage syndrome.