Short-term effect of pancreatic capsule and anterior layer of transverse mesocolon in radical gastrectomy and cancerometastasis factor analysis / 中国医师进修杂志

ABSTRACT

ObjectiveTo investigate the short-term effect of pancreatic capsule and anterior layer of transverse mesocolon in radical gastrectomy and analyze the cancerometastasis factor.MethodsA total of 288 gastric cancer patients were randomly assigned into two groups145 cases in observation group and 143 cases in control group.The patients only in observation group were given the pancreatic capsule and anterior layer of transverse mesocolon resecting during radical gastrectomy.The pancreatic capsule and anterior layer of transverse mesocolon were histologically analyzed for metastasis.The data including the operation time,blood loss during operation,number of dissected lymph nodes and postoperative complications were analyzed in both groups.ResultsThere were no significant differences between two groups in the blood loss during operation and postoperative complications (P ＞ 0.05).The operation time in observation group was longer than that in control group [ (2.9 ± 1.2) h vs.(2.3 ± 0.9) h,P =0.036],the number of dissected lymph nodes in observation group was more than that in control group(20.5 ±7.5 vs.13.5 ±9.3,P =0.005).The metastasis to the pancreatic capsule and/or anterior layer of transverse mesocolon were diagnosed in 12 cases(8.3％,12/145) in observation group.The metastasis to the pancreatic capsule and/or anterior layer of transverse mesocolon were found to be associated with tumor location,clinical staging,invasion depth and degree of lymph node metastasis (P =0.039,0.022,0.041,0.009),but not with gender,age,tumor position,tumor diameter and pathological classification (P ＞ 0.05).ConclusionsThe resection is beneficial to the patients with advanced gastric cancer staging relatively late because of potential metastasis.The pancreatic capsule and anterior layer of transverse mesocolon should be legitimately resected in radical gastrectomy.