Analysis of functional splenic artery blood flow embolization in the treatment of hypersplenism / 中国综合临床

ABSTRACT

Objective To retrospectively analyze the efficacy and safety of splenic embolization in the treatment of hypersplenism.Methods Thirty-six cases of hepatocellular carcinoma patients with cirrhosis,splenomegaly and hypersplenism underwent hepatocellular carcinoma embolization as well as with spleen embolization.White blood cells (WBC) and platelets were tested and postoperative clinical reactions were observed at 3,7,30 days and 3-6 months after the operation.Results The number of WBC and platelet were both significantly increased after the operation,the difference was significantly statistical [WBC3 d( 9.4 ±2.1 ) × 109/L,7 d(9.3 ± 2.3 ) × 109/L,30 d( 8.6 ± 2.1 ) × 109/L,3 months( 6.4 ± 1.6 ) × 109/L vs (2.6 ± 1.4) × 109/L,P＜0.01;platelet3 d(94 ±23) × 109/L,7 d(140 ±32) × 109/L,30 d(136 ±38) ×109/L,3 months( 119 ±26) × 109/L vs (32 ± 18) × 109/L,P＜0.01].All patients got fever,loss of appetite,nausea and pain in the spleen,of which 6 patients needed clinical treatment to control symptoms and left pleural effusion occurred in 3 patients,but without cases with serious complications.Conclusion The functional splenic artery blood flow embolization is a safe and effective treatment for liver cirrhosis caused by hypersplenism.