Investigation of lung cancer susceptibility correlated with polymorphism of DNA repair gene XRCC and hOGG1 / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 642-644, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-421094
ABSTRACT
DNA repair gene polymorphism can change the functions and efficiency of DNA repair,influence cancer susceptibility.Many studies have been reported that DNA damage repair gene polymorphisms may be related to cancer susceptibility mutation in a variety of tumors and plays an important role in the pathological process.In addition,DNA damage repair genes may interact with other genes,the combined effect of tumor occurrence,development.Lung cancer is the well-studied tumor in this respect.In this paper,DNA damage repair gene XRCC and hOGG1 polymorphisms biological characteristics,these gene single nucleotide polymorphisms as well as cancer susceptibility were reviewed to provide a theoretical basis for the tumor prevention,diagnosis and treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS