SIRT1 and neoplasms / 国际肿瘤学杂志
Journal of International Oncology
; (12): 569-572, 2011.
Article
in Zh
| WPRIM
| ID: wpr-421686
Responsible library:
WPRO
ABSTRACT
SIRT1 (Sirtuin type 1 ), a member of histone deacetylase, dependents on nicotinamide adenine dinucleotide ( NAD + ). It involves in the covalent modification of histones, participates in tumor development and progression through transcription, translation and post-translational modification and so on. Therefore, the expression of SIRT1 in tumor cells or abnormal function could be one of the important mechanisms of tumor development, and may become a new potential therapeutic target for neoplasms.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Journal of International Oncology
Year:
2011
Type:
Article