Clinical analysis of borderline ovarian tumor with 60 cases / 中国医师进修杂志

ABSTRACT

ObjectiveTo investigate the clinical features of borderline ovarian tumor (BOT).MethodThe clinical features, clinical stage, malignant potential, pathological type, the positive rate of serum CA125 were analyzed in 60 patients with pathological diagnosis of BOT. ResultsSerous cystadenoma was the main pathological type, accounted for 60.0％ (36/60). The occurrence of focal canceration in serous cystadenoma[22.2％ (8/36)]was higher than that in mucinous cystadenoma[5.3％(1/19)](P＜ 0.05). The positive rate of CA125 was 51.7％(31/60). The positive rate of CA125 in BOT with　micro-dip or focal canceration[65.0％(13/20) and 81.8％(9/11)]was higher than that in simple BOT [31.0％(9/29)](P＜O.05),but there was no significant difference between BOT with micro-dip and BOT with focal canceration (P＞ 0.05 ). ConclusionsBOT is low malignant potential and preoperative diagnosis is difficult because of the typical clinical symptoms. CA125 is not sensitive to pure BOT. Women of childbearing age should regularly check for ovarian tumor by ultrasonography and preoperative serum CA125 test can be combined with micro-dip on the BOT and those made with preoperative focal predict cancer diagnosis. Aggressive surgical treatment is necessarily as soon as possible and rapid intraoperative pathological examination to reduce cancer risk.