Activating transcription factor 4 in malignant tumors and drug resistance / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 735-737, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-422198
ABSTRACT
Activating transcription factor 4 ( ATF4),one of the activating transcription factors,belongs to the cyclic AMP response element binding protein family.The expression of ATF4 is up-regulated by tumor micro-environmental factors.And ATF4 regulates the processes of tumor growth,infiltration,metastasis,apoptosis and drug resistance.Therefore,ATF4 might serve as a potential therapeutic target in cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2011
Type:
Article
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