Comparison of the risk factors for anterior circulation and posterior circulation ischenic strokea retrospective case series study / 国际脑血管病杂志

ABSTRACT

Objective To investigate the differences of the vascular risk factors for anterior circulation and posterior circulation ischemic stroke.Methods The unified diagnosis and treatment questionnaires of ischemic stroke in Qingdao city were developed.The data of 943 consecutive patients with acute ischemic stroke treated in the Departments of Neurology in 11 hospitals with imaging facilities such as computerized tornography (CT) or magnetic resonance imaging (MRI) in Qingdao city and its surrounding counties from June 2008 to February 2009 were retrospectively collected.The risk factors for anterior circulation and posterior circulation ischemic stroke were analyzed.Results Univariate analysis showed that there were significant differences in the age,sex,history of coronary heart disease,hyperlipidemia,atrial fibrillation and basdine National Institutes of Health Stroke Scale (NIHSS) score between anterior circulation and posterior circulation ischermic stroke (all P ＜0.05).Multivariate logistic regression analysis showed that the age (odds ratio [ OR ] 1.025,95％ confidence interval [ CI ] 1.009-1.042) and the baseline NIHSS score (OR 1.052,95％ CI 1.019-1.086) tended to the interior circulation ischernic stroke,whereas coronary heart disease (OR 0.512,95％ CI 0.341-0.768) and hyperlipidemia (OR 0.585,95％ CI 0.386-0.884) tended to posterior circulation ischemic stroke,and hyperlipidemia was an independent risk factors for posterior circulation ischemic stroke.Conclusions Vascular risk factors exerted different effects on anterior circulation and posterior circulation ischemic stroke.