Effect of mild hypothermia on β2-microglobulin level in cerebrospinal fluid of traumatic brain injury patients / 国际外科学杂志
International Journal of Surgery
;
(12): 742-744, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-422256
ABSTRACT
Objective To study the effect of mild hypothermia on β2- microglobulin (MG) level in cerebrospinam(CSF) of traumatic brain injury (TBI) patients.Methods Thirty-six severe TBI patients were divided into two groups randomly,mild hypothermia treatment group and normathermia treatment group,and the β2- MG level and GOS score in CSF of these patients in different time- point were evaluated.Results β2-MG level increased at first,then decreased gradually,and MBP level in mild hypothermia group decreased greater than the control group( P < 0.05 ),moreover,patients in mild hypothermia treatment group had better outcome than the control group( P < 0.05).Conclusion Mild hypothermia may act as neuroprotection by inhibiting inflammatory response or improving immune regulation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Surgery
Year:
2011
Type:
Article
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