Clinical comparison of propofol combined with pentazocine or fentanyl on analgesic artificial abortion / 中国医师进修杂志

ABSTRACT

ObjectiveTo investigate the effects of propofol combined with pentazocine or fentanyl on analgesic artificial abortion.MethodsOne hundred and thirty cases of early pregnancy were divided into fentanyl-propofol group (group A) and pentazocine -propofol group (group B) with 65 cases each by random digits table.The change of systolic pressure,diastolic pressure,heart rate,breathing rate,pulse oxygen saturation (SpO2) was compared,anesthetic induce time,operation time,awaking time,adverse effect was recorded.ResultsSystofic pressure,breathing rate and SpO2 intraoperative in two groups was significantly lower than that before anesthesia(P＜ 0.05 ),breathing rate,SpO2 intraoperative in group A was significantly lower than that in group B (P ＜ 0.05 ).The incidence of respiratory depression in group A was significantly higher than that in group B [20.0％(13/65) vs.6.2％(4/65)](P＜0.05).ConclusionPentazocine combined with propofol anesthesia used in analgesic artificial abortion lead to less incidence of adverse reactions,which is a more effective and safe method.