Effect of right ventricular end-diastolic diameter on prognosis of patients with chronic heart failure / 中国综合临床

ABSTRACT

Objective To determine the prognostic value of fight ventricular end-diastollc diameter (RVDD)in patients with chronic heart failure(CHF).Methods The clinical data of the in-hospital patients diagnosed as CHF were analyzed retrospectively.Telephone follow-up was carried out for all participants.The patients were divided into the survival group and death groups according to their clinical outcomes.The relationship between RVDD and death was evaluated by independent t-test and multivariate Logistic regression analysis.Results 1552 in-hospital patients were enrolled into the study.The mean age was 64.62 ± 10.45 years old,with 879(56.64％)male.After 3 years' follow-up,439(28.29％)patients died.Comparison of baseline data showed that gender,age,SBP,NYHA classification,the serum level of creatinine,LVEF,LVDD and RVDD were significantly different between the two groups(P ＜ 0.01);Multivariable logistic analysis showed that RVDD(OR=1.11,95％ CI1.07-1.14,P ＜0.01),age(OR =1.03,95％ CI1.02-1.05,P ＜0.01),creatinine(OR =1.02,95 ％ CI1.01-1.04,P ＜ 0.01),LVEF(OR =0.93,95 ％ CI0.92-0.97,P ＜ 0.01),LVDD(OR =1.13,95％ CI1.09-1.17,P ＜0.01)and NYHA classification(OR =1.17,95％ CI1.12-1.24,P ＜ 0.01)were independent predicting factors for the death of CHF patients.The power of RVDD to predict mortality was examined by ROC curves.The area under the curve was 0.805(95％ CI0.798-0.812,P ＜ 0.01).Conclusion RVDD increases the risk of death in patients with CHF.RVDD is a significant independent predictor for death among patients with CHF.