Study on the anti-fatigue effect by taurine / 中国综合临床

ABSTRACT

Objective To evaluate the anti-fatigue effect by taurine in mice.Methods Mice were randomly divided into three groups,two groups were given taurine at dose of 10.0 g/L and 2.5 g/L respectively,and the control group was given physiological Saline.After 30 days of intervention,the swimming test was carried out,the liver glycogen,serum BUN and Lactic acid were also measured.Results Both high taurine and low taurine prolonged the swimming time significantly comparing with the control group ([380.9 ± 65.5 ] s vs [226.0 ± 44.8 ] s vs [175.7 ± 24.4 ] s,P ＜ 0.05 ).Liver glycogen also increased significantly,they were ( 21.85 ± 4.21 ),( 13.26 ± 2.16 ) ( 7.13 ± 1.34 ) mg/g in high,low taurine and control group respectively.The level of BUN and LAC were decreased significantly in taurine groups ( P ＜ 0.05 ).Conclusion Taurine may has the anti-fatigue effect to some extent.