Preparation and properties of porous co-substituted calcium polyphosphate scaffold as bone repair material* / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
;
(53): 7045-7048, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-423814
ABSTRACT
BACKGROUND:
Ions doping is an important method for the modification of bioceramic.OBJECTIVE:
To evaluate a novel co-substituted bioceramic scaffolds as bone repair material.METHODS:
The microstructure and crystallization of the scaffolds were detected by scanning electron microscope and X-ray diffraction. Compression strength test,degradation test and cell culture experiment were assumed to evaluate the properties of KSCPP in vitro. After a short period of muscle pouches implantation,the performance of KSCPP in vivo was evaluated.RESULTS ANDCONCLUSION:
The results show that KSCPP scaffold has a higher compressive strength and degradation rate. Moreover,the MTT assay and implantation test reveal that the KSCPP scaffold exhibits lower cytotoxicity and better tissue biocompatibility than CPP and HA. The study proved the great potential of KSCPP in bone repair applications.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Tissue Engineering Research
Year:
2011
Type:
Article
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