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Aneurysmal Neck Clipping as the Primary Treatment Option for Both Ruptured and Unruptured Middle Cerebral Artery Aneurysms
Journal of Korean Neurosurgical Society ; : 269-275, 2016.
Article in English | WPRIM | ID: wpr-42447
ABSTRACT

OBJECTIVE:

Although middle cerebral artery (MCA) aneurysms are less amenable to coil embolization, an increasing number of studies support favorable endovascular treatment for them. The purpose of this study is to compare the outcomes of two different treatments (surgery versus coiling) and evaluate the benefits of surgical clipping for MCA aneurysms.

METHODS:

Here we retrospectively analyzed the outcomes of 178 ruptured and unruptured MCA aneurysms treated in patients between September 2008 and April 2012. Parameters assessing treatment outcomes include degree of aneurysm occlusion, presence of regrowth, clinical status, and complications.

RESULTS:

Among 178 MCA aneurysms, 153 were treated surgically. After a mean follow-up of 12 months, the surgery group showed a clinically significant complete occlusion rate (98%) compared with the coiling group (56%) (p<0.001). Follow-up radiologic evaluation showed a higher regrowth rate (four of 16 cases) in the coiling group than in the surgery group (one of 49 cases) (p=0.003). There was no statistically significant difference in favorable clinical outcome rate between the two groups. The procedure-related permanent morbidity and mortality rates were 2% (three of 153 cases) in the surgery group and 0% (0 of 25 cases) in the coiling group.

CONCLUSION:

Compared to endovascular treatment, surgical neck clipping for both ruptured and unruptured MCA aneurysms results in a significantly higher complete obliteration rate and less regrowth. Therefore, even in this endovascular era, we still recommend surgical clipping as the primary treatment option for MCA aneurysms rather than coil embolization.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Surgical Instruments / Intracranial Aneurysm / Retrospective Studies / Follow-Up Studies / Mortality / Middle Cerebral Artery / Embolization, Therapeutic / Aneurysm / Neck Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: Journal of Korean Neurosurgical Society Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Surgical Instruments / Intracranial Aneurysm / Retrospective Studies / Follow-Up Studies / Mortality / Middle Cerebral Artery / Embolization, Therapeutic / Aneurysm / Neck Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: Journal of Korean Neurosurgical Society Year: 2016 Type: Article