Correlation factor analysis in older type 2 diabetes patients with osteoporosis / 中国医师杂志

ABSTRACT

ObjectiveTo investigate the correlation factors in older type 2 diabetes patients with osteoporosis.MethodsThe related risk factors including their age,body mass index(BMI),history of disease and bone mineral density(BMD) were analyzed in 106 older type 2 diabetes patients with osteoporosis,who were hospitalized in the first affiliated hospital of Guangzhou Medical College during January 2000 to December 2010.Results BMD of lumbar[ (0.756 ± 0.099) g/cm2 ],neck of femur [ (0.658 ± 0.111 ) g/cm2 ] and wards triangle [ (0.525 ± 0.064) g/cm2 ] in the eighty group were distinctly reduced than the sixty group[ (0.883 ±0.112)g/cm2,(0.781 ±0.130) g/cm2,(0.627 ±0.118) g/cm2] ( P ＜0.05).BMD of lumbar[ (0.738 ± 0.114) g/cm2 ) ] and neck of femur [ ( 0.664 ± 0.112 ) g/cm2 ) ] in low weight patients ( BMI≤20 kg/m2 ) were distinctly reduced than normal BMI group [ ( 0.816 ± 0.138 ) g/cm2,( 0.727 ±0.134)g/cm2] ( P ＜0.05).BMD of lumbar[ (0.743 ±0.122) g/cm2] and neck of femur[ (0.719 ±0.147)g/cm2] in patients with course of diabetes more than 10 years were distinctly reduced than the patients with less course[ (0.886 ± 0.132 ) g/cm2,( 0.792 ± 0.122 ) g/cm2 ] ( P ＜ 0.05 ).BMD was negatively correlated with age and history of diabetes ( P ＜ 0.05 ).BMD was positively correlated with BMI ( P ＜ 0.05).ConclusionsOlder,low BMI and long history of diabetes are the risk factors of older type 2 diabetes patients with osteoporosis.