Influence of nursing intervention on insulin resistance and pancreatic β- cell function of patients with diabetes mellitus / 中国实用护理杂志

ABSTRACT

Objective To investigate the influence of nursing intervention on insulin resistance and pancreatic β-cell function of patients with diabetes mellitus. Methods 90 patients with type 2 diabetes treated in our hospital from March to December 2010 were chosen as the research object.All patients were randomly divided into the control group (40 cases)and the intervention group (50 cases).The hospitalized patients in the control group were taken conventional treatment methods for treatment.The patients in the intervention group were given nursing intervention on the basis of conventional therapy.The situation of the change of FBG,2hBG,HbAlc,INS,HOMA-IR,HOMA-β before treatment,before discharge and 6 months after follow-up were compared.The influence of nursing intervention on insulin resistance and pancreatic β-cell function were evaluated comprehensively. Results After treatment for the patients of the two groups,the indicators all improved before discharge.FBG,2hBG,HbAlc and HOMA-IR all decreased significantly,while INS,HOMA- β increased significantly.The improved level of the observation group was more significant.The improved values of the two groups showed significant difference. Conclusions Taking appropriate nursing interventions based on routine treatment for diabetic patients aiming at problems arising in their course of treatment can effectively reduce the patients' insulin resistance and improve β-cell secretory function,and enhance the overall effect.