Detection of food allergen-specific IgE and IgG in patients with chronic urticaria / 中华皮肤科杂志
Chinese Journal of Dermatology
;
(12): 203-204, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-425109
ABSTRACT
Objective To evaluate the roles of food allergen detection in patients with chronic urticaria.Methods Food allergen-specific IgE and IgG were detected in 502 patients with chronic urticaria and 100 normal human controls.Double-blind,placebo-controlled food challenge (DBPCFC) test was performed in patients who were proved to be positive or negative for food-specific IgG or IgE.Results Food-specific IgE was detected in 37.45% (188/502) of the patients,with cashew,peanuts and soybeans as the most common allergens.The detection rate of food-specific IgG was 72.11% (361/502),with the major allergens being milk,egg,shrimp and crab.DBPCFC revealed false positivity and negativity in the detection of food-specific IgG and IgE.Conclusions Clinicians should pay attention to food allergen detection in the treatment of chronic urticaria,especially in the treatment of allergy mediated by IgG antibodies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
/
Diagnostic study
Language:
Chinese
Journal:
Chinese Journal of Dermatology
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS