The clinical observation of fluticasone salmeterol inhaler combined with salbutamol inhalation of oxygen-driven treatment of chronic obstructive pulmonary disease with acute exacerbation / 中国基层医药

ABSTRACT

Objective To observe the clinical efficacy of fluticasone salmeterol inhaler combined with salbutsmol inhalation of oxygen-driven treatment of chronic obstructive pulmonary disease with acute exacerbation.Methods 60 patients of chronic obstructive pulmonary disease with acute exacerbation,randomly divided into observation and control groups of 30 patients each.The control group on the basis of conventional treatment with salmeterol plus fluticasone inhalation powder compound and the oxygen-driven albuterol inhalation aerosol liquid,the other group by conventional therapy based on the use of oxygen-driven albuterol inhalation aerosol solution,then compare the clinical curative effects.Results There were 18 examples excellencely,10 examples improve,2 examples ineffective of observation group with total effective rate 93.3％ ; 9 examples excellencely,11 examples improve,10 examples ineffective of control group with total effective rate 66.7％.The contrast of total effective power with the two groups exists the statistical significance ( x2 =4.60,P ＜ 0.05 ) . In the observation group,FEV1 and FVC of post-treatment,were better than pretherapy and post-treatment of control group(t =2.629,2.649,2.064,2.051,P ＜0.05).Conclusion Salmeterol and fluticasone propionate inhalation powder hybrid atomizing inhalation of salbutamol effective than salbutamol alone.