Study on Stevens – Johnson syndrome (SJS) and Lyell syndrome (TEN) due to allergy of medication at the Department of Allergology and Clinical immunology in Bach Mai Hospital (1997-2002)
Journal of Medical Research
;
: 57-63, 2005.
Article
in Vietnamese
| WPRIM
| ID: wpr-4257
ABSTRACT
Study on 98 patients with SJS and Lyell were treated at the Department of Allergology and Clinical immunology in Bach Mai Hospital (1997-2002). SJS & TEN always occurred when patients used the ampicillin and antibiotics of beta-lactam family, carbamazepine and anti-convulsion drugs properly or not. The symptoms of SJS & TEN appeared late (1-7 days) with 9 common clinical symptoms such as mucous membrane ulcerations, erythema, bullas and fever, etc. SR, uremia, enzymes of liver cells and proteinuria went up, that were main changes in blood test and urine test of SJS & TEN patients. Treating time was long-lasting, for SJS was 14.298.83 days, for Lyell syndrome is 19.716.6 days, with 4 main drugs methyl-prednisolon, dimedrol, glycerin borate, and 5% glucose solution. There was no dead at that time.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmaceutical Preparations
/
Stevens-Johnson Syndrome
/
Hypersensitivity
Language:
Vietnamese
Journal:
Journal of Medical Research
Year:
2005
Type:
Article
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