Research on aberrant expression of HOX in gastrointestinal neoplasms and its mechanism / 国际外科学杂志
International Journal of Surgery
; (12): 396-399, 2012.
Article
in Zh
| WPRIM
| ID: wpr-426087
Responsible library:
WPRO
ABSTRACT
Homebox genes are known to determine cell proliferation and differentiation and subsequently regulate the occurrence,development and prognosis of many tyhpes of malignant tumors in human.Some recent studies have shown that homebox genes are abnormally expressed in the esophageal,gastric,coloreetal and other gastrointestinal tumors.In this review,we consider that homebox genes may regulate the occurrence,development of gastrointestinal tumors by interacting with transcription factors in vivo and abnormal epigenetic modifications.Therefore,homebox genes are closely related to gastrointestinal tumors.
Full text:
1
Index:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
International Journal of Surgery
Year:
2012
Type:
Article