Small Non-coding Transfer RNA-Derived RNA Fragments (tRFs): Their Biogenesis, Function and Implication in Human Diseases
Genomics & Informatics
;
: 94-101, 2015.
Article
in English
| WPRIM
| ID: wpr-42766
ABSTRACT
tRNA-derived RNA fragments (tRFs) are an emerging class of non-coding RNAs (ncRNAs). A growing number of reports have shown that tRFs are not random degradation products but are functional ncRNAs made of specific tRNA cleavage. They play regulatory roles in several biological contexts such as cancer, innate immunity, stress responses, and neurological disorders. In this review, we summarize the biogenesis and functions of tRFs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Organelle Biogenesis
/
RNA
/
RNA, Transfer
/
Neurodegenerative Diseases
/
RNA, Untranslated
/
Immunity, Innate
/
Nervous System Diseases
Limits:
Humans
Language:
English
Journal:
Genomics & Informatics
Year:
2015
Type:
Article
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