Study of the relationship between serum-ascites albumin gradient and esophageal-gastric fundus variceal bleeding / 中国基层医药

ABSTRACT

ObjectiveTo study the relationship between serum-asicites albumin gradient(SAAG) and the portal hypertensive ascites in order to appreciate the value of SAAG on the prediction of esophageal-gastric fundus variceal bleeding.Methods34 patients with cirrhotic ascites were examined with endoscopy.The patients were classified as high-gradient group and low-gradient group by the SAAG value of 11g/L.The relationship between SAAG and esophageal-gastric fundus varices was studied by Pearson correlation analyasis.Among the 34 patients studied,10 patients had esophageal-gastric fundus variceal bleeding and 24 patients had no esophageal-gastric fundus variceal bleeding.ResultsIn the 30 patients classified as high-gradient group,22 patients had esophageal-gastric fundus variceas.In the 4 patients classified as low-gradient group,no patient had esophageal-gastric fundus variceas.The results showed the direct correlation between the level of SAAG and the degree of esophageal-gastric fundus variceas ( r =0.81,P ＜0.01 ).The mean level of SAAG in bleeding group,consisting 10 patients,was (24.18 ±7.36) g/L.The mean level of SAAG in non-bleeding group,consisting 24 patients,was ( 18.19 ± 6.18)g/L.The results showed sig nificant difference between the bleeding group and non-bleeding group(P ＜0.05).ConclusionThere is correlation between the level of SAAG and the portal venous pressure.The level of SAAG is valueable on the prediction of esophageal-gastric fundus variceal bleeding.