Efficacy and safety evaluation on the treatment of coronary artery disease with Shexiang-baoxin pill and complex Danshen drop pill / 国际中医中药杂志

ABSTRACT

ObjectiveTo evaluate the clinical effect and safety of coronary artery disease (CAD) treated with Shexiang-baoxin pill and Complex Danshen drop pill.MethodsArticles of randomized controlled trials (RCTs) about the treatment of CAD with Shexiang-baoxin pill and Complex Danshen drop pill were retrieved and the quality of these studies were analyzed by RevMan 5.1.6 software with Meta analysis.Results Seven studies involving 603 patients were included.The results of meta-analysis showed that the experimental group was better in ameliorating angina symptoms of angina pectoris patients [RR=1.33,95％CI (1.21,1.45),P＜0.01 ] and ECG [RR=1.55,95％CI (1.34,1.79),P＜0.01 ] than the control group.Adverse reaction rate of the experimental group and the control group was 6.85％ and 14.38％ respectively,the difference was not statistically significant (P＞0.05).ConclusionThe existing researches demonstrated that Shexiang-baoxin pill was better in treating CAD angina pectoris than Complex Danshen drop pill.