Hypoxia inducible factor-1α and tumor / 国际肿瘤学杂志

ABSTRACT

Hypoxia inducible factor-1α(HIF-1α) is usually highly expressed in tumor cells,and can promote tumor growth.HIF-1α is correlated with tumor condition,the diagnosis and the prognosis.Therefore,HIF-1α can be used for tumor treatment in the level of transcriprion,pro-transcriprion and target.It is possible to improve the treatment efficiency,and to lengthen patients lifespan.