Significance of microsatellite instability in colorectal cancer / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 935-938, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-429843
ABSTRACT
Microsatellite instability (MSI) is an important molecular mechanism in colorectal cancer's initiation and progression,which has significant clinical significance.MSI is a diagnostic biomarker for Lynch synchrome.Moreover,the clinical implication of MSI testing extends to the role of prognostic marker and predictive maker,due to the better outcome of patients with MSI positive colorectal cancer and a general lack of response to chemotherapy employing 5-fluorouracil.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2012
Type:
Article
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