The correlation between the adiponectin gene SNP+276G/T, SNP+45T/G with metabolic syndrome / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 911-913, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-430342
ABSTRACT
Two hundred and twenty-four patients with metabolic syndrome (MS) and 200 subjects as normal controls were included in this study.Genotyping of +276G/T,+45T/G SNPs in apM1 gene was made by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique,and then the distribution and differences in genotypes and allele frequencies in the population were observed.It was found that the G/T polymorphism of +276 site was associated with MS,while +45 T/G polymorphism had nothing to do with MS.It is suggested that the +276G/T polymorphism may be a predisposing factor of MS.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2012
Type:
Article
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