Value of stepwise therapy of dehydration drugs on aged people with cerebral contusion / 中国综合临床

ABSTRACT

Objective To explore the advantage of stepwise therapy of dehydration drugs on aged people with cerebral contusion for reduce the incidence of delayed traumatic intracranial hematoma and improve neurological function.Methods One hundred and twenty standard patients were divided into stepwise therapy group(n =60,group A) and regular therapy group(n =60,group B) by randomly.In group A,according to the developing regularity of cerebral edema,we use less dehydration drugs on early stage,and increase the dose step by step with the disease developed.In group B,we use dehydration drugs regularly,then compare the incidence rate of delayed traumatic intracranial hematoma and the cure rate of the disease between this two groups.Results The incidence of delayed traumatic intracranial hematoma was 8％ (5/60) in A group,and 30％ (18/60) in B group.Compared with B group,the stepwise therapy of dehydration drugs on cerebral contusion can reduce the incidence of delayed traumatic intracranial hematoma obviously,there was significant difference between two groups(x2 =6.21,P ＜0.05) ;The recovering rate was 70％ (42/60) in B group,and 30％ (28/60) in B group,there was significant difference between two groups (x2 =6.72,P ＜ 0.05).Conclusion The treatment of stepwise therapy is more reasonable on aged people with cerebral contusion,the incidence of delayed traumatic intracranial hematoma can be reduced obviously compared with regular therapy of dehydration drugs.