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Meta-analysis on laparoscopy-assisted total gastrectomy for gastric cancer / 中华普通外科杂志
Chinese Journal of General Surgery ; (12): 1014-1019, 2012.
Article in Chinese | WPRIM | ID: wpr-430873
Responsible library: WPRO
ABSTRACT
Objective To evaluate the safety and efficacy of laparoscopy-assisted total gastrectomy (LATG) for gastric cancer by systematic review and meta-analysis.Methods The literature database before February,2012 was extensively searched to retrieve the comparative studies of LATG and open total gastrectomy(OTG) with a relevance of study goal.The inclusion and exclusion criteria were formulated.Aftera quality evaluation,the data was extracted.The Cochrane collaboration RevMan 5.1 version software was used for meta-analysis.Results There are ten studies meeting the inclusion criteria for meta-analysis.The total sample size of these studies was 942 cases.Compared to OTG,LATG experienced longer operation time [weighted mean difference(WMD) =41.12 min,95% confidence interval(CI)20.62-61.63,P <0.01)],less blood loss(WMD =-198.36 ml,95% CI-300.94--95.78,P < 0.01),earlier time to flatus(WMD =-0.80 days,95% CI-1.17--0.42,P<0.01),shorter hospital stay(WMD =-4.02days,95% CI-6.03--2.01,P < 0.01) and decrease in overall complications [relative risk (RR) =0.55,95% CI0.40-0.76,P < 0.01)].The number of dissected lymph nodes,proximal or distal resection margin and mortality were similar between the two groups.Conclusions Laparoscopy-assisted total gastrectomy is a safe and feasible procedure with less blood loss,less overall complications and quick recovery.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Systematic reviews Language: Chinese Journal: Chinese Journal of General Surgery Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Systematic reviews Language: Chinese Journal: Chinese Journal of General Surgery Year: 2012 Type: Article