PCR-based techniques for the detection of minority mutations / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
;
(12): 40-45, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-431174
ABSTRACT
With the development of molecular biology and molecular genetics,more attention has been taken to the advanced techniques which can be used to detect minority mutations.In recent years,many techniques such as amplification refractory mutation system,PCR clamping,pyrophosphorolysis-activated polymerization,co-amplification at lower denaturation temperature-PCR and digital PCR have been developed,which will make the hereditary disease diagnosis,cancer detection,noninvasive antenatal diagnosis step into a new stage in the near future.This review presents an overview of the principles,aoolications,advantages and disadvantages of these techniques.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Journal of Laboratory Medicine
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS