The Effect of Bucillamine of Trace Element Levels of Hair in Patients with Rheumatoid Arthritis / 대한류마티스학회지
The Journal of the Korean Rheumatism Association
;
: 126-132, 1995.
Article
in Korean
| WPRIM
| ID: wpr-43159
ABSTRACT
OBJECTIVES:
We investigated the changes of trace element levels in hair of patients with rheumatoid arthritis after bucillamine treatment.METHODS:
We performed inductively coupled plasma atomic emission spectrometry in determination of trace element levels in hair of patients with rheumatoid arthritis.RESULTS:
The results were as follows 1) There was a significant increase of copper concentration, but no change in zinc level after bucillamine treatment. 2) There were no significant changes in copper and zinc concentrations between the proximal and distal portions of hair after long-term bucillamine treatment.CONCLUSIONS:
Our results showed the significant increase of copper level and no significant change of zinc level in hair after bucillamine treatment, but, although statistically not significant, copper and zinc levels were decreased on experiment with divided hair. So, our findings do not permit any conclusion on the influence of bucillamine on trace element levels in hair. Further studies in large samples and comparison with the effect of D-penicillamine will be necessary to clarify the association of trace element levels in hair of rheumatoid arthritis patients and bucillamine treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Penicillamine
/
Plasma
/
Arthritis, Rheumatoid
/
Spectrum Analysis
/
Zinc
/
Copper
/
Hair
Limits:
Humans
Language:
Korean
Journal:
The Journal of the Korean Rheumatism Association
Year:
1995
Type:
Article
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