Your browser doesn't support javascript.
loading
Observation on the influence of Shenqi-Fuzheng injection on T-lymphocyte subsets, NK cell and the leukocyte of the patients with advanced gastric cancer / 国际中医中药杂志
International Journal of Traditional Chinese Medicine ; (6): 22-24, 2013.
Article in Chinese | WPRIM | ID: wpr-431594
ABSTRACT
Objective To explore the term efficacy and the influence on the immune function and hemotology toxicity of Shenqi-Fuzheng injection to advanced gastric cancer patients combined with SP chemotherapy.Methods 53 patients with advanced gastric cancer were randomly divided into an observation group (26 cases) and a control group (27 cases).All patients were treated in the oncology department of the Chinese People's Liberation Army 264th Hospital during 2010.1 ~2012.6.The observation group accepted SP chemotherapy plus Shenqi-Fuzheng injection and the control group was treated with SP chemotherapy.After 2 cycles of chemotherapy the term efficacy was evaluated,cellular immune function index and hemotology adverse reaction were observed.Results The objective response rate (RR) between the treatment group and the control group had no difference (x2=0.024,P>0.05).After 2 cycles of treatment,CD3+ (64.09±7.59)%,CD4+ (44.17±6.09)%,CD8+ (27.60±7.64)%,CD4+/CD8+ (1.63±0.66) and NK(28.07±7.28)% in the observation group were higher than the control group [accordingly (54.64 ± 6.39) %,(35.01 ± 6.05) %,(24.29 ±7.41) %,(1.30 ± 0.72),(25.06 ± 7.24) %,(P< 0.05)].The incidence of leukocyte decline in the observation group was 19.23%,and 44.44% in the control group.There was significant difference (P<0.05).Conclusion Shenqi-Fuzheng injection plus SP chemotherapy can improve the cellular immune function and the tolerance to chemotherapy and reduce hemotology adverse of patients with advanced gastric cancer.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Traditional Chinese Medicine Year: 2013 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Traditional Chinese Medicine Year: 2013 Type: Article