Influence of CRRT on the functions of monocyte in patients with severe acute renal failure / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 56-58, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-431848
ABSTRACT
Objective To investigate the effect of continuous renal replacement therapy (CRRT) on the function of monocyte in patients with severe acute renal failure (ARF).Methods The function of monocyte in 42 patients with ARF accepting CRRT was dynamically observed and compared with that of healthy people.Results Cytokine secreting function of monocyte in patients with ARF was stronger than that in healthy people[TNF-α(1 212.61 ±107.43) vs (857.34 ±83.45) ng/L,IL-6(2 518.22 ±228.22) vs (1 948.13 ±218.23) ng/L,IL-8(416.18 ±54.46) vs (229.31 ± 39.83) ng/L] (t =6.47,7.09,6.45,all P < 0.05) 48 h after CRRT,cytokine secreting function declined to normal.Conclusion CRRT corrects the disorder of cytokine secreting function of monocyte in patients with ARF,decreases the inflammation response.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Primary Medicine and Pharmacy
Year:
2013
Type:
Article
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