Efficacy analysis of singulair combined with zithromax in the treatment of children with asthma / 中国基层医药

ABSTRACT

Objective To observe the clinical effect of singulair (montelukast sodium chewable tablets) combined with Zithromax(Azithromycin for Suspension) in treatment of children with asthma.Methods 86 children with asthma were randomly divided into control group and observation group,each group 43 cases,observation group was treated with singulair and zithromax,and control group was only treated with singulair.Before and after treatment,pulmonary function and clinical efficacy were observed.Furthermore,clinical symptoms disappearance time and the incidence of adverse reactions were also observed.Results After teratment,FEV1 and PEF in observation group were significantly higher than control group(P ＜ 0.05).The total effective rate in observation group and control group were 97.7％ and 88.9％,respectively.The difference between two groups was statistically significant(P ＜0.05).Observation group coughing,shortness of breath and wheeze and other symptoms disappeared time were shorter than the control group(P ＜ 0.05).Adverse reactions between the two groups had no significant difference (P ＞ 0.05).Conclusion Singulair combined with zithromax in the treatment of chronic pelvic inflammatory disease with a better therapeutic effect.It was worthy of clinical application.