Association between exposure to antimicrobial household products and allergic symptoms
Environmental Health and Toxicology
; : e2014017-2014.
Article
in En
| WPRIM
| ID: wpr-43248
Responsible library:
WPRO
ABSTRACT
OBJECTIVES: Antimicrobial chemicals are used in a variety of household and personal care products. Exposure to antimicrobial household products has been hypothesized to lead to allergic diseases in children. METHODS: We investigated antimicrobial household product exposure and allergic symptoms in Korean children. An antimicrobial exposure (AE) score was derived. To examine the symptoms of allergic diseases (current wheeze, current rhinitis, and current eczema) in the past 12 months, we used a questionnaire based on the core module of the International Study of Asthma and Allergies in Children. Complete data for the analysis were available for 25,805 of the 35,590 (72.5%) children. RESULTS: The prevalence of current allergic diseases was as follows: wheeze, 5.6%; allergic rhinitis, 32.6%; and eczema, 17.7%. The mean (standard deviation) AE score was 14.3 (9.3) (range: 0-40). Compared with subjects with a low AE score (reference), subjects with a high AE score (fourth quartile) were more likely to have symptoms of wheezing and allergic rhinitis (adjusted odds ratio [aOR] for wheezing 1.24, 95% confidence interval [CI], 1.05-1.45, p for trend=0.24; aOR for allergic rhinitis 1.30, 95% CI, 1.20-1.40, p<0.01). CONCLUSIONS: These findings suggest that frequent use of antimicrobial household products was associated with current wheeze and current allergic rhinitis.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Asthma
/
Triclosan
/
Odds Ratio
/
Respiratory Sounds
/
Rhinitis
/
Family Characteristics
/
Prevalence
/
Surveys and Questionnaires
/
Eczema
/
Household Products
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Child
/
Humans
Language:
En
Journal:
Environmental Health and Toxicology
Year:
2014
Type:
Article