Dexamethasone and calcium gluconate auxiliary oxytocin in preventing postpartum hemorrhage / 中国基层医药

ABSTRACT

Objective To investigate the clinical effect of the dexamethasone combined with 10％ calcium gluconate auxiliary hormone oxytocin to prevent postpartum benorrhage.Methods 128 patients were randomly divide into two groups,control group (n =64)intramuscular injection 20 u oxytocin after delivery of the fetus;observation group(n =64)after entering the secind stage of labor,do a quick infusion with a 5％ glucose 100 ml + 10％ of the calcum gluconate 10ml,intramuscylar injection 20 u oxytocin + dexamethasone 10 mg after deliver of the fetus.The clinical effects were compared in two groups of prevention of postpartum hemorrhage.Results Both the postpartum 2 h bleeding of observation group[(153.2 ±43.1) ml] and the postpartum 24 h bleeding[(419.3 ± 77.8) ml] were lower than that of the control group[(265.2 ± 86.2) ml,(550.6 ± 99.1) ml] (t =2.553,3.869,all P ＜ 0.01) ; The time of second stage and third stage of labor for the observation group [(26.6 ± 11.1) min,(6.8 ± 1.8) min] were lower than that of the control group [(55.4 ± 12.4) min,(19.8 ± 3.2) min] (t =3.452,3.213,all P ＜ 0.01).Conclusion The effect of dexamethasone combined with 10％ calcium gluconate auxiliary hormone oxytocin to prevent postpartum hemorrhage is aplus,which can be pronted and applied in clinic.