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Anti-inflammatory and Analgesic Effects of Combined Application of Glucosamine and Chondroitin Sulfate / 中国运动医学杂志
Article in Zh | WPRIM | ID: wpr-432567
Responsible library: WPRO
ABSTRACT
Objective To investigate the anti-inflammatory and analgesic effects of combined application of glucosamine(GS)and chondroitin sulfate(CS).Methods The acute and chronic anti-inflammatory effects of combined application of GS and CS were observed respectively through carrageen-induced paw edema and cotton-induced inguinal granuloma of rats.The analgesic effect of combined application of GS and CS was investigated by the mouse pain model induced by 0.6% acetic acid Results As compared with the control group,the degree of paw edema and the weight of granuloma in combined application of GS and CS group were significantly reduced(P<0.05 and P<0.01,respectively);and the writhing number of mice decreased significantly(P<0.05).Conclusion Combined application of glucosamine and chondroitin sulfate demonstrates obviously anti-inflammatory and analgesic effects.
Key words
Full text: 1 Index: WPRIM Language: Zh Journal: Chinese Journal of Sports Medicine Year: 2010 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: Chinese Journal of Sports Medicine Year: 2010 Type: Article