Anti-inflammatory and Analgesic Effects of Combined Application of Glucosamine and Chondroitin Sulfate / 中国运动医学杂志
Chinese Journal of Sports Medicine
; (6): 313-315, 2010.
Article
in Zh
| WPRIM
| ID: wpr-432567
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WPRO
ABSTRACT
Objective To investigate the anti-inflammatory and analgesic effects of combined application of glucosamine(GS)and chondroitin sulfate(CS).Methods The acute and chronic anti-inflammatory effects of combined application of GS and CS were observed respectively through carrageen-induced paw edema and cotton-induced inguinal granuloma of rats.The analgesic effect of combined application of GS and CS was investigated by the mouse pain model induced by 0.6% acetic acid Results As compared with the control group,the degree of paw edema and the weight of granuloma in combined application of GS and CS group were significantly reduced(P<0.05 and P<0.01,respectively);and the writhing number of mice decreased significantly(P<0.05).Conclusion Combined application of glucosamine and chondroitin sulfate demonstrates obviously anti-inflammatory and analgesic effects.
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WPRIM
Language:
Zh
Journal:
Chinese Journal of Sports Medicine
Year:
2010
Type:
Article