Prediction of Long-term Response to Cardiac Resynchronization Therapy by Real-time Three-dimensional Echocardiography / 中国医科大学学报
Journal of China Medical University
;
(12): 752-754, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-432616
ABSTRACT
Objective To evaluate the value of real-time three-dimensional echocardiography(RT3DE)to predict the long-term response to cardiac resynchronization therapy(CRT).Methods Twenty-six patients with heart failure were scheduled for CRT.RT3DE was performed before and one year after the pacemaker implantation,and left ventricular(LV)dyssynchrony was defined as the maximum difference(Tmsv 16-Dif)and standard deviation(Tmsv 16-SD)when the minimum systolic volume of 16 segments was reached.Patients were divided into re-sponders and non-responders according to a reduction ≥15 % in LV end-systolic volume(LVESV)after CRT.Results Seventeen patients(65.4 %)were classified as responders.Compared with non-responders,the responders demonstrated a significant increase in LV ejection fraction,and reduction in Tmsv 16-SD.Tmsv 16-SD was a determinant factor for Δ LVESV ≥15%.Tmsv 16-SD 〉3.5% could be employed to evaluate the short-term response to CRT with 80 % sensitivity and 77 % specificity.Conclusions CRT can increase the LV systolic function and synchrony.RT3DE is highly predictive for long-term response to CRT
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of China Medical University
Year:
2010
Type:
Article
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