Multidrug resistance mediated by ABCG2 / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 403-406, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-433386
ABSTRACT
ABCG2 is a member of the ATP-binding cassette (ABC) transporter family.The overexpression of ABCG2 is identified as one of the important mechanisms that limiting cellular accumulation of various compounds.With regard to its broad substrate spectrum including various anticancer drugs and environmental carcinogens,the function of ABCG2 is associated with multidrug resistance (MDR) and tumor development.ABCG2 as a target site to reverse MDR has been widely concered.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2013
Type:
Article
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