Isolation and Genetic Study of Hantavirus from Apodemus penibsulae Captured in Yeuncheon-gun, Kyunggi-do
Journal of the Korean Society of Virology
;
: 337-345, 1998.
Article
in Korean
| WPRIM
| ID: wpr-43341
ABSTRACT
Hantaviruses are distributed in rodent population world-widely even in geographical areas where hemorrhagic fever with renal syndrome (HFRS) has not been reported. Va.ictus species of Family Muridae and Arvicolidae serve as the natural reservoirs of hantaviruses. Hantaan virus, Seoul virus, Puumala virus, Prospect Hll virus, Sin Hombre virus and New York virus are members of genus Hantavirus and isolated from lungs of A. agrarius, C glareolus, M. pennsylvanicus, P. maniculatus and P. leucopus respectively. This experiment was intended to find the distribution of hantavirus infection among wild rodents and isolate the hantavirus from lung tissue of seropositve Apodemus peninsulae, and compared the nucleotide and amino acid sequences with prototype of hantaan virus 76-118 strain. Hantaviral sequences were amplified from lung tissues of A. peninsulae by reverse-transcriptase polymerase chain reaction. Alignment and comparison of the 324 nucleotide of G2 region of M-genomic segment diverged 4.6% and 0% at the nucleotide and amino acid levels, and complete N protein-coding region of S-genomic segment diverged 3.7% and 1.4% nucleotide and amino acid levels, respectively. This is the report to spill-over on the hantaan virus from A. peninsulae to A. peninsulae in Korea.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rodentia
/
Polymerase Chain Reaction
/
Amino Acid Sequence
/
Orthohantavirus
/
Hantaan virus
/
Hantavirus Infections
/
Puumala virus
/
Seoul virus
/
Murinae
/
Hemorrhagic Fever with Renal Syndrome
Limits:
Animals
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Society of Virology
Year:
1998
Type:
Article
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