Accuracy of auditory evoked potential index in monitoring depth of sevoflurane anesthesia in infants / 中华麻醉学杂志

ABSTRACT

Objective To evaluate the accuracy of auditory evoked potential index (AAI) in monitoring the depth of sevoflurane anesthesia in infants.Methods Fifty ASA Ⅰ or Ⅱ pediatric patients,aged 1-3 yr,scheduled for elective surgery under general anesthesia,were enrolled in this study.Anesthesia was induced with propofol,cisatracurium and remifentanil.The patients were tracheal intubated and mechanically ventilated.PET CO2 was maintained at 35-45 mm Hg.Anesthesia was maintained with inhalation of sevoflurane.Fresh gas flow was first set at 6 L/min for 15 min and then reduced to 3 L/min.The end-tidal sevoflurane concentration (CETSev) was maintained at 2.5%,2.8%,3.0%,3.5%,3.7% and 4.0%.Each CETSev was maintained for 3 min.AAI was continuously monitored before induction of anesthesia,after induction,immediately before sevoflurane inhalation,and at the 6 CET Sev.Results AAI was negatively correlated with CET Sev (r =-0.872,P ＜ 0.01).Conclusion AAI can accurately reflect the depth of sevoflurane anesthesia in infants.