Clinical Evaluation of Netilmicin Sulfate in Treating Lower Respiratory Tract Infections / 医药导报

ABSTRACT

Objective: To observe the effectiveness of neltimicin sulfate in treating the infections of lower respiratory tract.　Methods: 41 cases of lower respiratory tract infections served as observation subjects (treated with netilmicin sulfate 200 mg*d-1, iv drip) while the other 30 cases as control subjects (treated with penicillin 8×109 U*d-1 and ampicillin 8.0 g*d-1, iv drip).　Results: The therapeutic effectiveness was significantly higher in the observation group than that in the control group (P＜0.01). The sensitivity tests of isolates from the sputum showed that 71.1% of the isolates were highly sensitive to netilmicin sulfate, 28.9% moderately sensitive to netilmicin sulfate. The total effectiveness rate was 97.6%.　Conclusion: Netilmicin sulfate is effective in treating the lower respiratory tract infections and causes less side effects.