Clinicopathological analysis and genetic diagnosis of subcutaneous panniculitic T-cell lymphoma / 临床与实验病理学杂志
Chinese Journal of Clinical and Experimental Pathology
;
(12): 113-116, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-433903
ABSTRACT
Purpose To explore the clinicopathological features of subcutaneous panniculitic T-cell lymphoma(SPTCL) and significances of genetic analysis in the diagnosis. Methods Histopathology, immunohistochemitry and detection of clonal gene rearrangement by PCR were used in 3 cases of subcutaneous panniculitic T-cell lymphoma (SPTCL), which were originally diagnosed as relapsing nodular nonsuppurative panniculitis. Results Three misdiagnostic cases were correctly redefined as subcutaneous panniculitic T-cell lymphoma, with immunophenotype of CD45+,CD45RO+, Mac387-,and clonal TCR-β gene rearrangement. Conclusions Subcutaneous panniculitic T-cell lymphoma has distinctive clinicopathological features. Genetic analysis is an effective method for the diagnosis of SPTCL.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Journal of Clinical and Experimental Pathology
Year:
2001
Type:
Article
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