Expressions of ER, PR and CerbB-2 in papillary thyroid carcinoma and their clinical significances / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 339-341, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-434329
ABSTRACT
Objective To explore the expressions of ER,PR and CerbB-2 in human papillary thyroid carcinoma,and their correlation with the clinical features.Methods The expressions of ER,PR and CerbB-2 were detected by immunohistochemistry in 89 papillary thyroid carcinoma samples and 13 nodular goiter samples.Results In papillary thyroid carcinoma samples,ER,PR and CerbB-2 were detected for 50.56 %(45/89),43.82 % (39/89),24.72 % (22/89),respectively.In nodular goiter,ER,PR and CerbB-2 were detected for 15.38 % (2/13),7.69 % (1/13),0,respectively,there were significant differences between the two groups (x2 =5.649,P=0.017,x2 =6.211,P=0.013,x2 =4.097,P=0.043).The positive rates of PR were 56.26 %(26/46) in without lymph node metastasis,compared with those lymph node metastasis 30.2 3% (13/43) were significantly higher,the difference was statistically significant (x2 =6.239,P =0.012).Conclusion The expressions of ER,PR and CerbB-2 are significant higher in papillary thyroid carcinoma.The detection of ER,PR and CerbB-2 might be helpful for early diagnosis and prognosis of papillary thyroid carcinoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Screening study
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS