Myloied derived suppressor cells and cancer / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 332-335, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-434405
ABSTRACT
Myeloid derived suppressor cells(MDSCs) are a subpopulation of immunosuppressive innate immune cells derived from bone marrow stem cells,which negatively regulate immune response in tumor progression.MDSCs have a powerful suppressive function and significant heterogeneity.They can modulate innate and adaptive immune responses through a variety of mechanisms to promote the development of tumor,and also facilitate angiogenesis and metastasis of tumor via non immunologic mechanisms.In recent years,as increasingly mature research for the differentiation,proliferation and suppressive function of MDSCs,the derived researches of MDSC-targeted tumor immunotherapy will finally contribute to increasing the efficiency of vaccine and tumor therapy in the future.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS