The clinical significance of total serum bile acid test in evaluation of the prognosis of posthepatitis cirrhosis / 中国基层医药

ABSTRACT

Objective To explore the clinical significance of serum total bile acid (TBA) test in evaluation of the prognosis of posthepatitis cirrhosis.Methods 92 patients with posthepatitis cirrhosis were selected as the observation group,and divided into A,B,C groups according to the Child-Pugh grades.32 healthy people were selected as the control group.The level of serum TBA was detected and compared.Results The level of TBA in the observation group was (84.26 ±49.03) μmol/L,which was higher than that in the control group[(3.52 ± 2.67) μmol/L](t =17.53,P ＜ 0.01).The level of TBA was gradually increased in Child-Pugh grade A,B,C grade,and the differences were statistically significant (t =3.84,6.21,5.49,all P ＜ 0.05).Conclusion TBA test is benefit for the diagnosis and prognosis of posthepatitis cirrhosis.