Clinical study on the timing of postoperative parenteral nutrition support in patients of gastrointestinal neoplasms / 中华普通外科杂志

ABSTRACT

Objective To evaluate the timing of postoperative parenteral nutrition support for gastrointestinal tumor patients with a definite nutritional risk.Methods Using a randomized control clinical research methods,80 gastrointestinal cancer patients were randomly divided into study group (40 cases) and control group (40 cases).In the study group parenteral nutrition support started on postoperative day 2,while in the control group it started on postoperative day 1.Flatus passing,the rate of infectious complications,the rate of systemic inflammatory response syndrome,postoperative nutrition support related expenses,and the duration of postoperative hospital stay were recorded.Results There was no significant differences between the two groups (P ＞ 0.05) in age,sex,body mass index,use of glutamine,disease and type of surgery.Compared with the control group,patients in the study group had earlier postoperative flatus passing [(3.33± 1.10) d vs.(4.03 ± 1.51) d,P =0.020],less systemic inflammation response syndrome (8/40 vs.17/40,P =0.030),shorter postoperative hospital stay [(3.33±1.10) d vs.(4.03±1.51) d,P=0.020] and lower nutrition support costs [(2144.49 ±1210.96) RMB vs.(2915.99 ± 1615.68) RMB,P =0.018].There was no significant difference in postoperative nutrition index,peristalsis recovery time and infectious complications between the two groups (all P ＞ 0.05).Conclusions In patients undergoing surgery for GI tumors,parenteral nutrition support started on post-op day 2 promotes the recovery of gastrointestinal function,while decreasing medical cost.