Population-based Incidence and Survival for Primary Central Nervous System Lymphoma in Korea, 1999-2009 / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
;
: 569-574, 2015.
Article
in English
| WPRIM
| ID: wpr-43515
ABSTRACT
PURPOSE:
Primary central nervous system lymphoma (PCNSL) is an uncommon brain tumor accounting for 2%-5% of all primary brain tumors. Few population-based analyses of survival for patients with PCNSL have been conducted, particularly in Asian countries. MATERIALS ANDMETHODS:
Using the Korea National Cancer Incidence Database, 1,062 cases of PCNSL newly diagnosed from 1999 to 2009 were analyzed. The crude rate, age-standardized rate (ASR), and annual percent change were calculated. To estimate the observed survival, we restricted the data to between 1999 and 2007 and followed the cases until December 2010. The overall survival was estimated using the Kaplan-Meier method, and piecewise Poisson regression model.RESULTS:
The ASR for PCNSL between 1999 and 2009 was 0.17 per 100,000, and the annual percent change from 1999 to 2009 was 8.8% (p < 0.001). The ASR of males was higher than that of females, and the older groups (60s or over) showed the largest increase in incidence rates. For all ages, the five-year survival from PCNSL was 29.9% between 1999 and 2007. Survival from PCNSL is known to show strong association with age at diagnosis.CONCLUSION:
These results are similar to those of previous studies. Our findings may be helpful to clinicians and patients in determining long-term prognoses for PCNSL.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Brain Neoplasms
/
Central Nervous System
/
Registries
/
Incidence
/
Asian People
/
Diagnosis
/
Korea
/
Lymphoma
Type of study:
Diagnostic study
/
Incidence study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Cancer Research and Treatment
Year:
2015
Type:
Article
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