Current progress of MDM2 inhibitor in urological malignancies / 国际外科学杂志
International Journal of Surgery
;
(12): 318-322, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-435279
ABSTRACT
The discovery of the key negative regulator MDM2 and the detailed mechanism of MDM2-P53 protein-protein interaction provide a great opportunity to activate P53 by inhibiting MDM2-P53 interaction with MDM2 inhibitor.In this article,the author will review the accomplishment in the area of MDM2 inhibitor treatment on tumors of urological system.The detailed mechanism and the signal pathways involved are summarized simultaneously.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Surgery
Year:
2013
Type:
Article
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