Analysis of 300 cases of adverse drug reactions and treatment cost / 国际中医中药杂志

ABSTRACT

Objective To analyze 300 cases of adverse drug reaction (ADR) distribution and the cost for the past two years.Methods Original data of 300 ADR eases from 2011 to 2012 in our hospital and drug used for treatment of ADR were statistically analyzed; and the amount of money spent on drugs treating ADR was calculated.Results In 300 cases of ADR reports,intravenous injections caused ADR incidence (87.00％) max,far higher than other routes of administration.and ADR caused by anti-infective drugs ranked first.ADR clinical manifestations in the majority of skin reactions such as hives,rash,swelling,anaphylactic shock,followed by the digestive system,nervous system and cardiovascular system.Costs of medicines for the treatment of ADR were analyzed and found 168 cases of ADR occurred after the treatment cost was 81,538.8 yuan,an average of 485.35 yuan,and the highest one used for a patient was 3023.68 yuan.Conclusion It would be helpful to reduce or prevent ADR occurrence,improve the drug rational use through strengthen ADR and drug safety monitoring.