Tendon allograft transplantation repairs Achilles tendon rupture / 中国组织工程研究

ABSTRACT

BACKGROUND:For the treatment of Achil es tendon rupture, peripheral ankle autologous tendon displacement is the traditional method in clinic, while the source of autologous tendon is limited, has damage to the donor site and has to pay with the normal power and stable structure. Al ogenic tendon has the advantages of rich sources, easy to obtain, no damage to the normal structure of the host, and can maintain its original biological structure. OBJECTIVE:To evaluate the clinical effect of tendon al ograft transplantation on the repair of Achil es tendon rupture. METHODS:Thirty cases of acute and old Achil es tendon rupture and four cases of chronic rupture with 2-5 cm deficiency were treated from August 2008 to June 2011. The cases were treated with tendon al ograft transplantation, and short leg cast was used to fix the limb after transplantation. Functional exercises were commenced at 4 weeks after cast removal. The clinical treatment results were evaluated by Arner-lindholm criteria. RESULTS AND CONCLUSION:The mean hospital stay was about 12.5 days. Twenty-five cases were fol owed-up for 1-3 years after transplantation and no rupture recurred. According to Arner-lindholm criteria, excel ent was in 25 cases, good in 3 cases, fair in 2 cases, and the excel ent and good rate was 92%. Ankle joint function was recovered to the normal level. Three cases had adhesion between Achil es tendon and adjacent tissue that had impact on the ankle dorsiflexion, and there was no significance decrease in foot pedal force. Two cases had rejection that healed after symptomatic treatment. One case had less flap margin necrosis and incision infection that healed after dressing and adjacent flap coverage. Incisions of al patients were healed at discharge. The results show that tendon al ograft transplantation has satisfactory effect for reaping the Achil es tendon rupture which is a recommended treatment option. But the long-term effect needs further observation.